PROTEINS and AMINO ACIDS

PBL SCENARIO: INTIMACY WITH NATURAL POLYMER:

GROUP 200 E PBL SCENARIO: INTIMACY WITH NATURAL POLYMER

GROUP MEMBERS:

GROUP MEMBERS Nkansah Betty Priscilla Baafi Mohammed Don Kudus Moro Safori Yaa Oparebea Edward Kyei-Acheampong Kodjo Arhin Jeffrey Johnny Arthur Komey Addaquay Frank Jemima Owusua Yeboah George Aidoo FACILITATOR: Dr. Victor Nuvor

PROBLEM STATEMENT :

PROBLEM STATEMENT An investigative report on Osu Children Home revealed the prevalence of malnutrition in children under 5 years leading to the stunted growth and mental underdevelopment of the children. There is a probability of the children becoming anaemic and prone to infection when they lack the amino acids needed in their food. Therefore, the need to managed the children with nutritional supplement and high protein diets.

OBJECTIVES:

OBJECTIVES Structure, types, properties and functions of amino acids, peptides and proteins. Relation of proteins with health and diseases.

AMINO ACIDS:

AMINO ACIDS An amino acid is the basic unit of a protein. 20 amino acids are used for synthesis of proteins.

STRUCTURE OF AMINO ACIDS :

STRUCTURE OF AMINO ACIDS C C O O – R H H 3 N +

TYPES AND CLASSIFICATION OF A.AS:

TYPES AND CLASSIFICATION OF A.A S TYPES: essential and non essential amino acids

Classification is based on their side chains: :

Classification is based on their side chains: Aliphatic group Hydroxyl group (-OH). Sulfhydryl group Acidic groups Basic group Aromatic group Imino group

OTHER CLASSIFICATIONS:

OTHER CLASSIFICATIONS

PROPERTIES OF AMINO ACIDS:

PROPERTIES OF AMINO ACIDS Acid-base property Optical property

BIOMEDICAL IMPORTANCE OF A.AS :

BIOMEDICAL IMPORTANCE OF A.A S For the synthesis of long chain polypeptides. Cellular functions; nerve transmission biosynthesis of porphyrins , purines , pyrimidines and urea.

PEPTIDE:

PEPTIDE Structure Properties Types Biomedical importance- Angiotensin II (Asp- Arg -Val-Tyr-Ile-His- Phe )

PROTEINS:

PROTEINS A protein is made up of a series of amino acids Synthesis of proteins is mRNA-directed. Protein synthesis occurs on ribosomes .

PROTEIN STRUCTURES:

PROTEIN STRUCTURES Primary Secondary Tertiary Quaternary structures - Leu - Tyr - Gly - Leu - Glu - Asn - Cys -

ROLES OF PROTEINS :

ROLES OF PROTEINS Structural Movement Protection Transport Source of Energy

RELATION OF PROTEINS IN HEALTH AND DISEASES:

RELATION OF PROTEINS IN HEALTH AND DISEASES

CONCLUSION:

CONCLUSION Proteins are indispensable and their deficiency can be very fatal to the body.

REFERENCES:

REFERENCES Champe and harvey : Lipponcott’s illustrated reviews biochemistry, 2 nd ed. Lipponcott’s Raven

Slide 19:

THANK YOU ! SHUKRAN !! PISHAA !!!