Strongest Herbal Pain Killers As Alternatives to Chemical Pain Relieve

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Strongest Herbal Pain Killers as Alternatives to Chemical Pain Relievers


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Strongest Herbal Pain Killers: As Alternatives For Chemical Pain Relievers Emily is your typical American bound in the corporate life during day time and back to her house before night time. But she has a terrible secret one that she keeps from her colleagues and relatives. Every night after she has tucked her kids to sleep and before she finally dozes off peacefully she takes oxycodone to manage her chronic hip and back pain. While this drug is available over the counter she takes it beyond the pre- scribed dosage by her physician. Her story is not uncommon millions of pain suferers have become dependent on pain killers According to a study done by NCCIH in 2012 around 25.3 million Americans suffer from chronic pain. In a separate study by ASAM they found out that a huge number of substance-related disorders are attributed to addiction on opioids. Of the 20.5 million Americans who have substance-abuse issues 2 million of those are addicted to pre- scription pain killers.

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The problem even persists in our brave soldiers who have to face pain management after their service. Around 44 of the US soldiers suffer from chronic pain and 15 rely on opioids to manage their pain. Such statistics can give one an insight of just how prevalent chronic pain is and opioid use is among the population. The problem with opioids and its derivatives Opioids act on the receptors of the central nervous system inhibiting their activation. This is how they provide for pain relief analgesia and relaxation to patients. Other mild side effects of opioids and its derivatives are nausea vomiting sweating and constipa- tion. The problem is that with continued use the individual can become dependent and would need higher dosage for the drug to still be effective. With improper dosage ad- verse side effects such as urinary retention delirium and even respiratory depression can occur. Turning to herbal pain killers According to a study done by NHS complementary health medicine is an emerging trend in America. Around 17.7 of the American population relies on herbal supple- mentation from 2007 to 2012. This means that a huge part of the general population is turning to herbal supplementation for their dietary needs. Unfortunately there are no published statistics yet on how prevalent is the use of herbal pain killers for the population. Perhaps this is an area that is under the radar of the public yet. Don’t worry as we got you covered. In this post we would shed some light into the most potent herbal pain killers. We would also discuss whether they can be alternatives for the chemical pain relievers we already know of.

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1. Corydalis Yanhusuo Common Name: Corydalis Learn More: Corydalis is a native herb in China the home of traditional medicine. Corydalis yanhusuo is just one of the many types of this herb. It has been gaining pop- ularity recently for its analgesic effects. The two main properties from the herb that are well-studied are dehydrocorybulbine and l-tetrahydropalmatine. The analgesic and sedative effects of corydalis yanhusuo can also be traced from these properties. How It Works: Generally corydalis yanhusuo works as an antagonist in the dopamine receptors. Both dehydrocorybulbine and l-tetrahydropalmatine are dopamine antago- nists specifically acting upon the D2 receptors of the body to increase the turnover of dopamine. By doing so they induce the release of dopamine and therefore modulate the pleasure pathway. The feeling of pain is therefore lessened as more dopamine is released by the body.

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Risks: Corydalis yanhusuo can cause sedation and even depression even on mild dosages. It is also not unusual to experience numbing and sleepiness as dopamine levels continue to fluctuate whilst on this medication. Pregnant and nursing women are also advised to avoid taking this medication. While the herb doesnt cause tolerance or dependency consult an expert in the field for proper dosage for your specific case pri- or to taking it. 2. Lactuca Virosa Common Name: Wild Lettuce Learn More: Lactuca virosa grows natively in Europe specifically in its central and southern regions. It can also be found in some parts of America India Iran and Pa- kistan. In the book Top 100 Food Plants written by Ernest Small it was discussed that wild lettuce was already known as an herb during the Roman era. It was regarded as a narcotic due to its milky latex substance. Image from Amazonia Exotics

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How It Works: The primary component of lactuca virosa is lactucin along with its de- rivatives of lactucopicrin. Lactucin acts as an agonist to the adenosine receptors specifically A1 and A2. Of the two its action on the A2 receptor is important for dopamine turnover and therefore the modulation of pain. Lactucopicrin is an antago- nist for the acetylcholinesterase receptors which means it prevents the break down of the enzyme. Acetylcholinesterase has some anti-inflammatory effects in the nervous system as well. Risks: This herb has mild sedative effects but in higher dosages can also cause rest- lessness. In this clinical study several patients were diagnosed with wild lettuce toxici- ty. Adverse side effects that were noted are agitation anxiety urinary retention ataxia and hallucinations. Possible reasons for the toxicity are the consumption of the herb without cooking and out of the harvesting season time. 3. Mitragyna Speciosa Common Name: Kratom Learn More: Mitragyna Speciosa is perhaps the most controversial herb in this post. Commonly referred to as kratom this herb can be found in the Southeastern Asian re- gion. Its opioid-like effects though has made it quite infamous. It has already been banned in various states in the US. In Asia countries like Malaysia and Thailand pro- hibit the selling buying or using of kratom. So it depends on where you’re from if you can use this herb as a pain reliever.

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Image from Uomo Vitruviano How It Works: Mitragynine is the main property of kratom. It works by binding to the μ-opioid receptors of the body. When it does so it produces analgesia and sedation. Mitragynine is a biased agonist of the μ-opioid receptors though. It signals the G pro- tein instead of the B-arrestin. Thus the possibility of experiencing tolerance and respi- ratory depression is lower as compared to chemical opioids. Risks: In low dosages kratom ingestion can lead to agitation anxiety or loss of ap- petite apart from its sedative and analgesic effects. With higher dosages there can be adverse reactions. Take the case of this man who took kratom outside the prescribed dosages for two weeks. He developed jaundice and pruritus because of such actions. Other side effects such as seizure kidney failure and pulmonary edema were also not- ed with the use of kratom though in conjunction with other drugs. 4. Nymphaea Caerulea Common Name: Blue Lotus

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Learn More: Originally nymphaea caerulea was native to Northeastern Africa. In fact the herb finds a mention on the Book of the Dead an ancient book of spells from Egypt. Back then the herb termed commonly as the blue lotus was regarded as an aphrodisiac. This herb also has many uses in traditional Ayurvedic medicine. It is only in recent years that its analgesic effects are being studied. This herb has been banned in countries of Latvia Poland and Russia. How It Works: Nymphaea Caerulea has two primary components which are the follow- ing: apomorphine and nuciferine. Apomorphine works as a dopamine receptor antago- nist which means it increases the turnover of dopamine. Again this can have modula- tory effects when it comes to the feeling of pain. On the other hand nuciferine is also a dopamine receptor antagonist but works mainly to inhibit motor movements. Risks: Some of the milder side effects of blue lotus are vomiting and hot flashes. If taken in conjunction with other stimulating drugs the side effects can be adverse.

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Symptoms such as euphoria hallucination and disorientation can be experienced. Do not take blue lotus with prescription medications as it can interact with them. 5. Petasites Common Name: Butterburs Learn More: Commonly found in marshy and moist areas petasites are yet another potent herbal alternatives that you can turn to. They are found in many regions of Asia and even America. Even during the ancient times petasites were used for fever pain and even headaches. Today it is a well known herb for treating migrates and many studies have already proved its effectiveness in treating this disease. Little known to many though is that petasites can also be effective in treating pain caused by inflam- mation.

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How It Works: Petasites work by inhibiting the lipoxygenase pathway and therefore suppressing the production of leukotrienes. This enzyme is one of the main modulators for inflammation. When it is released the inflammation process begins. In one study Petatewalide B was isolated from the herb and the researchers found out that this property have strong inhibitory effects to nitric oxide another modulator of inflamma- tion and pain. Risks: Make sure you get your petasites extracts from distinguished health stores. With improper preparation you can ingest the pyrrolizidine alkaloids from its stem. These alkaloids can cause hepatic toxicity to anyone who ingests them. 6. Piper Methysticum Common Name: Kava Kava Learn More: Kava kava is locally known as yaqona in Fiji. It is the national drink of the country. Its scientific name is piper methysticum and it is a part of the pepper family. In many countries this herb is regulated strictly. You might have issues with bringing kava kava to regions like Australia and Poland where there were news of its banning.

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Image from Forest Kim Starr How It Works: Piper methysticum works by inhibiting the COX pathways. It also sup- presses the production of NF-κB which is an important factor for the mediation of the inflammatory process. In a study by Smith and colleagues they separated the various properties of piper methysticum. They found out that the dihydrokavain property has anti-anxiety or sedative effects as well. Risks: Kava kava has been under the limelight for wrong reasons lately. In this study it was featured as one of the 21 herbs that can cause liver injuries when ingested. Simi- larly in this study it was designated as one of the “3Ks.” These three Ks are kratom kava kava and khat determined as the most potent herbal hepatotoxicity inducers. These herbs are not without their risks But then which medication doesnt have side effects It is important to research well about the information with regards to any medication you take. While these potent herbs have their downsides you also can’t dismiss their advantages. If you’re not suf- fering from heart conditions or youre not taking any other prescription medicines these alternatives might work well for you. Always remember that you have to follow the correct dosage. If you intend to use these herbs in their natural forms then you must follow the proper preparation procedures as well. If you’re buying online make sure you do so from a reputable health store. And finally it’s not bad to take advice from experts in the field such as physicians or botanists. There’s tons of blogs and websites online too which can help you when it comes to natural healing with herbs.

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