Chlorhexidine-An antiseptic bisguanide by Pharmaffiliates

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Chlorhexidine and related impurities – Role of Pharmaffiliates

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Chlorhexidine An antiseptic bisguanide By Pharmaffiliates

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Chlorhexidine - Introduction Antibacterial and antiseptic drug Belongs to Bisguanides family Efficacious against gram-negative, gram-positive bacteria and yeasts. Exists as cationic polybiguanide Used as diacetate or dihydrochloride salts

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Chlorhexidine -Medical uses Disinfectant of skin and hands Additive to creams, toothpaste, deodorants Preservative in eye drops In root canal irrigation in dental surgeries. A germicidal mouthwash

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Chlorhexidine -Mode of action Chlorhexidine   cation binds to the negatively charged bacterial cell wall. Bacteriostatic at low concentration Bactericidal at high concentration

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Chlorhexidine and related impurities – role of Pharmaffiliates Process related impurities are identified, characterized and isolated at Pharmaffiliates Identified as - Chlorhexidine diacetate impurity A, B, C, D, E, F, G, H, K, M, N, O, P.

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Chlorhexidine impurities Classification Chlorhexidine diacetate impurities A, B, C, D, G,H, M, N, P - Impurities in the commercial preparation of Chlorhexidine . Chlorhexidine diacetate Impurity F (N-(4-chlorophenyl)-urea) - Degradation product of Chlorhexidine in alkaline condition. Chlorhexidine diacetate Impurity K - Found in a study of the kinetics of Chlorhexidine hydrolysis. Chlorhexidine diacetate Impurity P (4-Chloroaniline)- Main degradation product of Chlorhexidine .

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Chlorhexidine and related impurities – Role of Pharmaffiliates All impurity standards are available pack size of 25mg and 50mg Competitive prices Customized pack sizes are available Complete structure elucidation and data interpretation NMR, MASS and Chromatographic purity along with detailed Certificate of Analysis.

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ThankYou FOR MORE DETAILS ABOUT PRODUCT VISIT https://pharmaffiliates.com/ YOU CAN ALSO ORDER THIS BY FILLING QUICK ENQUIRY FORM AT https://www.pharmaffiliates.com/send-enquiry

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