logging in or signing up BlastomycosisinDogs Elodie Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINTLite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 143 Category: Entertainment License: All Rights Reserved Like it (0) Dislike it (0) Added: November 16, 2007 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... Premium member Presentation Transcript Blastomycosis in Dogs: Blastomycosis in Dogs L. Joseph Wheat MiraVista Diagnostics, and Alfred M. Legendre University of Tennessee Dept of Veterinary MedicineEpidemiology: Epidemiology Proximity to water Outdoor activities Beaver dams Small outbreaks “Microfoci”Fungal Stain : Fungal Stain Clinical Findings & Involved Tissue: Clinical Findings & Involved Tissue Clinical findings Fever 62% Respiratory 49% Skin lesions 49% Depression 48% Anorexia 44% Ocular 43% Weight-loss 37% CNS 6% Involved tissues Lung 85% Lymph nodes 65% Eye 41% Skin 26% Bone 24% Cutaneous 13% Testes/GU 11% Brain 4%Radiographic Findings: Radiographic Findings Radiographic findings Nodulo interstit 39% Lymphadenop 29% Interstitial 22% Alveolar 9% Mass 9% Pleural 8% Normal 6% N=115, LSU Cutaneous and Bone Lesions: Cutaneous and Bone Lesions Other Common Manifestations: Other Common Manifestations Sensitivity of Cytology: Sensitivity of Cytology Tissue Node or abscess 52% Eye 7% Tracheal wash 6% Biopsy 9% Bone, node, sub-cutaneousAntigen Detection: Antigen Detection Antigen and Serology: Antigen and Serology Antigen % pos Urine 94 Serum 87 Antibody 76Antigen and Antibody Clearance : Antigen and Antibody Clearance Antigenuria During Relapse : Antigenuria During Relapse Sensitivity for Diagnosis: Sensitivity for Diagnosis Cytology 71-94% Antigen 94% Culture 10-20% Serology 41-83% Approach to Early Diagnosis: Approach to Early Diagnosis Tracheal washing Aspirate/biopsy lesions Antigen-urine, tracheal aspirates, other fluids SerologyOutcome of Treatment : Outcome of Treatment Improvement in Management: Improvement in Management Hightened awareness Early diagnosis Antigen, cytology, & serology AmB and Itra for severe disease Itra drug level monitoring Treatment more 4-6 months Monitoring antigen until negative Suppressive therapy if relapse Summary: Summary Early diagnosis important Histopathology Urinary antigen Amphotericin B and itraconazole Initially for severe cases Itraconazole treatment of choice Determine blood level Four to six months and until antigenuria clears Suppressive therapy if relapse You do not have the permission to view this presentation. In order to view it, please contact the author of the presentation.
BlastomycosisinDogs Elodie Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINTLite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 143 Category: Entertainment License: All Rights Reserved Like it (0) Dislike it (0) Added: November 16, 2007 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... Premium member Presentation Transcript Blastomycosis in Dogs: Blastomycosis in Dogs L. Joseph Wheat MiraVista Diagnostics, and Alfred M. Legendre University of Tennessee Dept of Veterinary MedicineEpidemiology: Epidemiology Proximity to water Outdoor activities Beaver dams Small outbreaks “Microfoci”Fungal Stain : Fungal Stain Clinical Findings & Involved Tissue: Clinical Findings & Involved Tissue Clinical findings Fever 62% Respiratory 49% Skin lesions 49% Depression 48% Anorexia 44% Ocular 43% Weight-loss 37% CNS 6% Involved tissues Lung 85% Lymph nodes 65% Eye 41% Skin 26% Bone 24% Cutaneous 13% Testes/GU 11% Brain 4%Radiographic Findings: Radiographic Findings Radiographic findings Nodulo interstit 39% Lymphadenop 29% Interstitial 22% Alveolar 9% Mass 9% Pleural 8% Normal 6% N=115, LSU Cutaneous and Bone Lesions: Cutaneous and Bone Lesions Other Common Manifestations: Other Common Manifestations Sensitivity of Cytology: Sensitivity of Cytology Tissue Node or abscess 52% Eye 7% Tracheal wash 6% Biopsy 9% Bone, node, sub-cutaneousAntigen Detection: Antigen Detection Antigen and Serology: Antigen and Serology Antigen % pos Urine 94 Serum 87 Antibody 76Antigen and Antibody Clearance : Antigen and Antibody Clearance Antigenuria During Relapse : Antigenuria During Relapse Sensitivity for Diagnosis: Sensitivity for Diagnosis Cytology 71-94% Antigen 94% Culture 10-20% Serology 41-83% Approach to Early Diagnosis: Approach to Early Diagnosis Tracheal washing Aspirate/biopsy lesions Antigen-urine, tracheal aspirates, other fluids SerologyOutcome of Treatment : Outcome of Treatment Improvement in Management: Improvement in Management Hightened awareness Early diagnosis Antigen, cytology, & serology AmB and Itra for severe disease Itra drug level monitoring Treatment more 4-6 months Monitoring antigen until negative Suppressive therapy if relapse Summary: Summary Early diagnosis important Histopathology Urinary antigen Amphotericin B and itraconazole Initially for severe cases Itraconazole treatment of choice Determine blood level Four to six months and until antigenuria clears Suppressive therapy if relapse