Methadone Ibogaine

Methadone and Ibogaine : Methadone and Ibogaine A Historical Comparison of Patient Status and Advocacy Issues Howard S. Lotsof


Background: Drug Control : Background: Drug Control • 1906 Pure Food and Drug Act • 1914 Harrison Narcotic Act • 1970 Controlled Substances Act


Background: Methadone : Background: Methadone • 1937 synthesized by Max Bockmühl and Gustav Ehrhart, I.G. Farbenindustries. Patent issued 1941 • 1950 use in treatment of opioid abstinence syndrome established in US • 1964 use in opioid maintenance therapy


Methadone molecule : Methadone molecule


Methadone powder : Methadone powder


Methadone diskets : Methadone diskets


Methadone liquid : Methadone liquid


Background: IbogaineAn experimental medication : Background: Ibogaine An experimental medication • Botanical source Tabernanthe iboga. Used for 100s of years in African medicine and religion • 1901 ibogaine isolated by Dybowski and Landrin • 1958 molecular structure determined Bartlett et al. • 1962 Lotsof discovers Antiaddictive effects


Ibogaine molecule : Ibogaine molecule


Tabernanthe iboga shrub : Tabernanthe iboga shrub


Roots contain ibogaine : Roots contain ibogaine


Pharmaceutical ibogaineexperimental medication : Pharmaceutical ibogaine experimental medication


Discovery of antiaddctiveeffects : Discovery of antiaddctive effects Methadone NYC 1964 Doctors administer to drugs users Ibogaine NYC 1962 Drug users administer to drug users


Methadone : Methadone The golden age of Dole and Nyswander 1966 - 1973


Drs. Dole and Nyswander ca 1976 : Drs. Dole and Nyswander ca 1976


Early generation methadone patients : Early generation methadone patients The program was administered or controlled by doctors in a medical research environment even at the clinic level. Nurses, counselors and patients believed in opioid maintenance therapy and collaborated to make it work. Patients and staff were a team. There was no “us” and “them”. Patients were treated like any other medical patients.


Early generation ibogaine patients : Early generation ibogaine patients A full collaboration between academic researchers, pharmaceutical developers and user self-help groups with mutual respect. Equal status between the parties. Users, doctors and drug developers worked together to define the ideal administration paradigm. There was no “us” and “them”. Patients were treated just like any other medical patients, except when they were treated like doctors.


Later generation ibogaine patients : Later generation ibogaine patients Drug users are no longer involved as equal participants in ibogaine development. Drug users and self-help groups, no longer affiliated with medical academics or drug developers, lost a level of authority and control. Ibogaine patients are not dependent on clinic administered drugs. Ibogaine providers generally leave the field rather than control or abuse patients. This could change in the future.


What’s wrong with methadone today? : What’s wrong with methadone today? Nothing is wrong with methadone. Almost something is wrong with many clinics that administer and provide it to patients. Medical decisions are often not made by medical doctors. Many clinics practice control of patients rather than providing them with ethical medical care.


Two important issues in methadone today : Two important issues in methadone today Stigma Discrimination


Stigma : Focuses attention on the victim Stigma


Discrimination: : Focuses attention on those who produce rejection and exclusion Discrimination:


Attention patients, counselors or methadone providers : If you are a methadone counselor or provider, please think for a moment and write on a piece of paper the words that come to mind when you think of methadone patients. If you are a methadone patient, please think for a moment and write on a piece of paper the words that come to mind when you think of methadone counselors, administrators or providers. Attention patients, counselors or methadone providers


Methadone 1.3 Internet program. Runs only on PCs will not run on a mac. : Methadone 1.3 Internet program. Runs only on PCs will not run on a mac.


Whether you are a patient, counselor or methadone provider, now write the words that come to mind when you view the methadone internet program. : Whether you are a patient, counselor or methadone provider, now write the words that come to mind when you view the methadone internet program.


Workshop Manual : Workshop Manual Lotsof/Dole letters Early Dole methadone paper History of Methadone Methadone patient reports Methadone physician reports Methadone research bibliography Review of Stigma and Discrimination Ibogaine patient experience History of ibogaine Ibogaine pharmacology