logging in or signing up news 20071122225647 Cinderella Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINTLite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 24 Category: Education License: All Rights Reserved Like it (0) Dislike it (0) Added: March 05, 2008 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... Premium member Presentation Transcript Slide1: What Lessons We Have Learnt from SARS Break in China？ Miao Xiaohui Ph. D & M.D. Vice President, Changzheng Hospital, Second Military Medical University Shanghai, P. R. China www.miaoxh.comSlide2: A email from professor Hou Jinlin at the beginning of February 2003 : Dear Prof. Miao: Recent months, a strange (mysterious) communicable disease is epidemic in Guangdong Province which is characterized with high fever, quick spreading, airway transmitting, high rate of HCWs infection and high mortality. Please tell and alert those experts and doctors who work at department of infectious diseases and respiratory diseases. www.miaoxh.comSlide3: Sorry, I nearly ignored it! www.miaoxh.comSlide4: What I did during the SARS outbreak in China? 2003.3.22: Sent two medical staff of Changzheng Hospital to Guangzhou to visit Southern Hospital. 2003.3.25: Gave a presentation titled “Pay high attention to atypical pneumonia” at the conference regarding to atypical pneumonia which was firstly held in Shanghai after SARS outbreak. 2003.3.30: I was invited to be a “consulting expert” by Health Bureau of Shanghai and thereafter attended numerous meetings organized by Health Bureau of Shanghai and Shanghai Medical Association. www.miaoxh.comSlide5: 2003.4: I was the head responsible for our hospital’s surveillance for suspicious, suspect and probable patients 2003.4.10: For the first time I attended a consulting activity for a imported SARS patient from Hong Kong. 2003.5.4-2003.6.23: As the commander, I lead a medical team including 72 members from SMMU to Beijing Xiaotangshan Hospital, where I spent a nervous, hard, challenging and unforgettable 50 days. www.miaoxh.com What I did during the SARS outbreak in China?Slide7: www.miaoxh.comSlide8: www.miaoxh.comSlide9: www.miaoxh.comSlide10: www.miaoxh.comSlide11: Morbidity and Mortality of SARS www.miaoxh.com Diagnosed Dead Cured Survived(％) Whole world 8437 812 7449 88.29 Mainland, China 5327 348 4941 92.75 Taiwan, China 671 84 506 75.41 Hong Kong, China 1755 298 1431 81.54 Xiaotangshan 680 8 672 98.80 Hospital Data till 7 October 2003Slide12: The lessons could be learnt from SARS break in mainland of China Lessons 1: Both ignorance and panic are unreasonable to a new emerging disease Lessons 2: General rules of infectious disease will not change a lot. Lessons 3: The roles played by government should be re- considered. Lessons 4: National and international collaboration as well as inter-laboratories is permanently needed Lessons 5: SARS CoV vaccine develop: a tasty dinner? or a deluxe banquet? www.miaoxh.comSlide13: Lessons 1: Both ignorance and panic are unreasonable to a emerging disease Government: Researchers: Clinicians: Medium: Public: www.miaoxh.comSlide14: Lessons 1: Both ignorance and panic are unreasonable to a emerging disease www.miaoxh.com Government Researchers Clinicians Medium PublicSlide15: Follow Koch’s rule: Multi-ways to transmit but in a main manner Clinical presentation may provide some clues Transmitting chain can be broken when proper measures are utilized Any causative agents infection always lead to different outcomes Is it not infectious during the latent period? What is the original reservoir? Rivet? Bat ?Or other wild animals? SARS “Gone with the wind”? www.miaoxh.com Lessons 2: General rules of infectious disease will not change a lot.Slide17: To be honest and tell pubic the truth at any time Do not interfere in researcher’s researches but support them Decision making should be based on the data from scientific survey and query a visible public health center is not equal to an invisible public health system ask experts and medical organization for making decision open up to the outside world Much more money is needed to establish and solid the public health system www.miaoxh.com Lessons 3: The roles played by government should be re-consideredSlide18: Government Researchers Clinicians Medium Public www.miaoxh.com Causing: Panic, disturbance, and losses in economy, politics and diplomacySlide19: Did patient’s blood samples belong to a single one or a single unit? Academic controversy: benefit or harmful? Keeping silence or speaking out? WHO: friendship? Or hostile? Why not joining the legal international network organization? www.miaoxh.com Lessons 4: National and international collaboration as well as inter-laboratories is permanently neededSlide21: Stage 1: early stage when SARS-CoV was discovered Stage 2: late stage when SARS has gone and dose not appear again Two questions remain to be answered: 1. How and can we prove the protectiveness of any kinds of vaccine? 2. Can and which animal model mimic human immune- response to SARS-CoV? www.miaoxh.com Lessons 5: SARS CoV vaccine develop: a tasty dinner? or a deluxe banquet?Slide22: Some questions should be cautiously answered 1. Is Osterporosis (thighbone necrosis) a often seen? 2. Does pulmonary fibrosis persistently advance in rehabilitation patient? 3. Can SARS-CoV be used as a bio-weapon in future local war? 4. What shall we do post SARS era? 5. Have lessons really been learnt and switched to be experience? 6. Can laboratory infection surely be prevented? 7. Are we prepared to another unprecedent new emerging infectious disease? 8. ……? www.miaoxh.comSlide23: As early as in the middle period of last century(1957) Pietrogrand reported the first case who had osteroporosis with complicated pathophyslogical mechanism caused by the overdose use of steroid. In SARS patients, osteroporosis were observed but fortunately it was not very common and not serious. Osteroporosis www.miaoxh.comSlide24: www.miaoxh.comSlide25: Since as high as 80% of SARS patients have interstitial lung damage, namely with acute lung injury (ALI) ,or even with acute respiratory distress syndrome (ARDS), it could be explained that pulmonary fibrosis may developed in recovered patients. Pulmonary Fibrosis www.miaoxh.comSlide26: Some questions should be cautiously answered 1. Is Osterporosis (thighbone necrosis) a often seen? 2. Does pulmonary fibrosis persistently advance in rehabilitation patient? 3. Can SARS-CoV be used as a bio-weapon in future local war? 4. What shall we do post SARS era? 5. Have lessons really been learnt and switched to be experience? 6. Can laboratory infection surely be prevented? 7. Are we prepared to another unprecedent new emerging infectious disease? 8. ……? www.miaoxh.comSlide27: Welcome to visit my website: www.miaoxh.com www.miaoxh.com You do not have the permission to view this presentation. In order to view it, please contact the author of the presentation.
news 20071122225647 Cinderella Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINTLite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 24 Category: Education License: All Rights Reserved Like it (0) Dislike it (0) Added: March 05, 2008 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... Premium member Presentation Transcript Slide1: What Lessons We Have Learnt from SARS Break in China？ Miao Xiaohui Ph. D & M.D. Vice President, Changzheng Hospital, Second Military Medical University Shanghai, P. R. China www.miaoxh.comSlide2: A email from professor Hou Jinlin at the beginning of February 2003 : Dear Prof. Miao: Recent months, a strange (mysterious) communicable disease is epidemic in Guangdong Province which is characterized with high fever, quick spreading, airway transmitting, high rate of HCWs infection and high mortality. Please tell and alert those experts and doctors who work at department of infectious diseases and respiratory diseases. www.miaoxh.comSlide3: Sorry, I nearly ignored it! www.miaoxh.comSlide4: What I did during the SARS outbreak in China? 2003.3.22: Sent two medical staff of Changzheng Hospital to Guangzhou to visit Southern Hospital. 2003.3.25: Gave a presentation titled “Pay high attention to atypical pneumonia” at the conference regarding to atypical pneumonia which was firstly held in Shanghai after SARS outbreak. 2003.3.30: I was invited to be a “consulting expert” by Health Bureau of Shanghai and thereafter attended numerous meetings organized by Health Bureau of Shanghai and Shanghai Medical Association. www.miaoxh.comSlide5: 2003.4: I was the head responsible for our hospital’s surveillance for suspicious, suspect and probable patients 2003.4.10: For the first time I attended a consulting activity for a imported SARS patient from Hong Kong. 2003.5.4-2003.6.23: As the commander, I lead a medical team including 72 members from SMMU to Beijing Xiaotangshan Hospital, where I spent a nervous, hard, challenging and unforgettable 50 days. www.miaoxh.com What I did during the SARS outbreak in China?Slide7: www.miaoxh.comSlide8: www.miaoxh.comSlide9: www.miaoxh.comSlide10: www.miaoxh.comSlide11: Morbidity and Mortality of SARS www.miaoxh.com Diagnosed Dead Cured Survived(％) Whole world 8437 812 7449 88.29 Mainland, China 5327 348 4941 92.75 Taiwan, China 671 84 506 75.41 Hong Kong, China 1755 298 1431 81.54 Xiaotangshan 680 8 672 98.80 Hospital Data till 7 October 2003Slide12: The lessons could be learnt from SARS break in mainland of China Lessons 1: Both ignorance and panic are unreasonable to a new emerging disease Lessons 2: General rules of infectious disease will not change a lot. Lessons 3: The roles played by government should be re- considered. Lessons 4: National and international collaboration as well as inter-laboratories is permanently needed Lessons 5: SARS CoV vaccine develop: a tasty dinner? or a deluxe banquet? www.miaoxh.comSlide13: Lessons 1: Both ignorance and panic are unreasonable to a emerging disease Government: Researchers: Clinicians: Medium: Public: www.miaoxh.comSlide14: Lessons 1: Both ignorance and panic are unreasonable to a emerging disease www.miaoxh.com Government Researchers Clinicians Medium PublicSlide15: Follow Koch’s rule: Multi-ways to transmit but in a main manner Clinical presentation may provide some clues Transmitting chain can be broken when proper measures are utilized Any causative agents infection always lead to different outcomes Is it not infectious during the latent period? What is the original reservoir? Rivet? Bat ?Or other wild animals? SARS “Gone with the wind”? www.miaoxh.com Lessons 2: General rules of infectious disease will not change a lot.Slide17: To be honest and tell pubic the truth at any time Do not interfere in researcher’s researches but support them Decision making should be based on the data from scientific survey and query a visible public health center is not equal to an invisible public health system ask experts and medical organization for making decision open up to the outside world Much more money is needed to establish and solid the public health system www.miaoxh.com Lessons 3: The roles played by government should be re-consideredSlide18: Government Researchers Clinicians Medium Public www.miaoxh.com Causing: Panic, disturbance, and losses in economy, politics and diplomacySlide19: Did patient’s blood samples belong to a single one or a single unit? Academic controversy: benefit or harmful? Keeping silence or speaking out? WHO: friendship? Or hostile? Why not joining the legal international network organization? www.miaoxh.com Lessons 4: National and international collaboration as well as inter-laboratories is permanently neededSlide21: Stage 1: early stage when SARS-CoV was discovered Stage 2: late stage when SARS has gone and dose not appear again Two questions remain to be answered: 1. How and can we prove the protectiveness of any kinds of vaccine? 2. Can and which animal model mimic human immune- response to SARS-CoV? www.miaoxh.com Lessons 5: SARS CoV vaccine develop: a tasty dinner? or a deluxe banquet?Slide22: Some questions should be cautiously answered 1. Is Osterporosis (thighbone necrosis) a often seen? 2. Does pulmonary fibrosis persistently advance in rehabilitation patient? 3. Can SARS-CoV be used as a bio-weapon in future local war? 4. What shall we do post SARS era? 5. Have lessons really been learnt and switched to be experience? 6. Can laboratory infection surely be prevented? 7. Are we prepared to another unprecedent new emerging infectious disease? 8. ……? www.miaoxh.comSlide23: As early as in the middle period of last century(1957) Pietrogrand reported the first case who had osteroporosis with complicated pathophyslogical mechanism caused by the overdose use of steroid. In SARS patients, osteroporosis were observed but fortunately it was not very common and not serious. Osteroporosis www.miaoxh.comSlide24: www.miaoxh.comSlide25: Since as high as 80% of SARS patients have interstitial lung damage, namely with acute lung injury (ALI) ,or even with acute respiratory distress syndrome (ARDS), it could be explained that pulmonary fibrosis may developed in recovered patients. Pulmonary Fibrosis www.miaoxh.comSlide26: Some questions should be cautiously answered 1. Is Osterporosis (thighbone necrosis) a often seen? 2. Does pulmonary fibrosis persistently advance in rehabilitation patient? 3. Can SARS-CoV be used as a bio-weapon in future local war? 4. What shall we do post SARS era? 5. Have lessons really been learnt and switched to be experience? 6. Can laboratory infection surely be prevented? 7. Are we prepared to another unprecedent new emerging infectious disease? 8. ……? www.miaoxh.comSlide27: Welcome to visit my website: www.miaoxh.com www.miaoxh.com