logging in or signing up Toxocara canis Charlo Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINTLite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: Embed: Flash iPad Dynamic Copy Does not support media & animations Automatically changes to Flash or non-Flash embed WordPress Embed Customize Embed URL: Copy Thumbnail: Copy The presentation is successfully added In Your Favorites. Views: 4123 Category: Entertainment License: All Rights Reserved Like it (5) Dislike it (0) Added: November 19, 2007 This Presentation is Public Favorites: 2 Presentation Description No description available. Comments Posting comment... By: dr00midoo (29 month(s) ago) good Saving..... Post Reply Close Saving..... Edit Comment Close By: Borma (42 month(s) ago) thanks very much Saving..... Post Reply Close Saving..... Edit Comment Close Premium member Presentation Transcript Slide1: Toxocara canis By: Nicole Bertram and Cory PolacekIntroduction: Introduction Most common worm parasite of dogs 10-40% of adults and 70% of puppies have the worm, but may show no clinical signs There are no specific breed susceptibilities 2-10% of Western Europeans have at some time been infected by this worm’s larvae The larva are the main cause of visceral larva migrans Background Information: Background Information Geographic Distribution: Worldwide Definitive host: Dogs and foxes Intermediate host: Mice and other mammals (not needed) Accidental host: Humans Morphology of Eggs: Morphology of Eggs Eggs are brownish in color and almost spherical They have surficial pits which make them sticky, allowing them to be transported long distances They are unembryonated when laid They can survive 2-4 years in cool, moist conditions Slide5: Alae are long and narrow, prominent in both sexes Males are 4-6 cm in length Females are 6.5 to more than 15 cm in length Morphology of Adult WormAdult continued: Adult continued Mouth of adult with three lipsLife Cycle: Life CycleLife Cycle: Life Cycle Adult worm found in small intestine of dog Eggs are passed in feces After 5-10 days the egg becomes embryonated and is infective Eggs is ingested and L2 larva hatches in small intestine Life Cycle: Life Cycle If ingested by puppy under 5 weeks of age: L2 larvae enter bloodstream and migrate through the heart and lungs In the lungs in molts into L3 L3 migrates up trachea and is ingested a second time Once in small intestine, it molts into adult Life Cycle: Life Cycle If eggs ingested by dog older than 5 weeks: L2 penetrate intestinal wall and migrate to various tissues The larvae encyst and become dormant Larvae become re-infective during pregnancy Larvae re-enter circulatory system and are carried to the placentas They then penetrate through to the fetal bloodstream and complete a lung migration en route to the small intestine for maturation Thus a puppy can be born with the infection Puppies can also become infected from their mother’s milk, but is not commonLife Cycle: Life Cycle If eggs ingested by human or mouse: In these hosts the L2 undergoes developmental arrest They can then wander to various organs and tissues in the body (liver, heart, lung, brain, muscle, eyes)-causing toxocariasis If puppy eats mouse, L2 completes maturation process If dog eats mouse, L2 goes dormant in tissue of dog and may be reactivated during pregnancyPathogenesis in Dogs: Pathogenesis in Dogs Adults are usually asymptomatic Puppies show clinical signs: Noisy breathing and Cough Nasal discharges Vomiting and Diarrhea Stunted growth rate Distended abdomen (pot belly) Pale mucous membranes Death is rare and is due to obstruction of intestine or ulceration and proliferation of intestinal wall Pathogenisis in Humans: Pathogenisis in Humans Many infections are asymptomatic The two main clinical presentations of Toxocariasis: Visceral larva migrans (VLM) Ocular larva migrans (OLM)Toxocariasis: Toxocariasis VLM Occurs mainly in preschool age children Larvae invade multiple tissues including the liver, heart, lungs, brain and muscles Symptoms include: Fever, anorexia, weight loss, cough, wheezing, rash, hepatosplenomegaly, and hypereosinophilia Severe cardiac, pulmonary, or neurologic involvement can occasionally cause deathToxocariasis: Toxocariasis OLM Occurs in older children and young adults Larvae cause inflammation and retinal scarring Symptoms include red eyes and impaired vision May cause partial permanent vision loss or complete blindnessDiagnosis in Dogs: Diagnosis in Dogs All puppies should be assumed to be infected Diagnosis of eggs in feces Eggs are not shed at all times, so false negatives are possibleDiagnosis in Humans: Diagnosis in Humans Detection of antibodies by ELISA Western-blot analysisTreatment in Dogs: Treatment in Dogs Puppies-anthelmintics MebendazoleTreatment in Humans: Treatment in Humans VML-antiparasitic drugs (albendazole or mebendazole) usually along with anti-inflammatory medications Control Measures: Control Measures Wash hands after touching soil or dogs Teach children not to eat dirt or to put dirty objects in their mouths Dogs should be wormed starting when they are 3 weeks old Prevent dog feces from contaminating the environment You do not have the permission to view this presentation. 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Toxocara canis Charlo Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINTLite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: Embed: Flash iPad Dynamic Copy Does not support media & animations Automatically changes to Flash or non-Flash embed WordPress Embed Customize Embed URL: Copy Thumbnail: Copy The presentation is successfully added In Your Favorites. Views: 4123 Category: Entertainment License: All Rights Reserved Like it (5) Dislike it (0) Added: November 19, 2007 This Presentation is Public Favorites: 2 Presentation Description No description available. Comments Posting comment... By: dr00midoo (29 month(s) ago) good Saving..... Post Reply Close Saving..... Edit Comment Close By: Borma (42 month(s) ago) thanks very much Saving..... Post Reply Close Saving..... Edit Comment Close Premium member Presentation Transcript Slide1: Toxocara canis By: Nicole Bertram and Cory PolacekIntroduction: Introduction Most common worm parasite of dogs 10-40% of adults and 70% of puppies have the worm, but may show no clinical signs There are no specific breed susceptibilities 2-10% of Western Europeans have at some time been infected by this worm’s larvae The larva are the main cause of visceral larva migrans Background Information: Background Information Geographic Distribution: Worldwide Definitive host: Dogs and foxes Intermediate host: Mice and other mammals (not needed) Accidental host: Humans Morphology of Eggs: Morphology of Eggs Eggs are brownish in color and almost spherical They have surficial pits which make them sticky, allowing them to be transported long distances They are unembryonated when laid They can survive 2-4 years in cool, moist conditions Slide5: Alae are long and narrow, prominent in both sexes Males are 4-6 cm in length Females are 6.5 to more than 15 cm in length Morphology of Adult WormAdult continued: Adult continued Mouth of adult with three lipsLife Cycle: Life CycleLife Cycle: Life Cycle Adult worm found in small intestine of dog Eggs are passed in feces After 5-10 days the egg becomes embryonated and is infective Eggs is ingested and L2 larva hatches in small intestine Life Cycle: Life Cycle If ingested by puppy under 5 weeks of age: L2 larvae enter bloodstream and migrate through the heart and lungs In the lungs in molts into L3 L3 migrates up trachea and is ingested a second time Once in small intestine, it molts into adult Life Cycle: Life Cycle If eggs ingested by dog older than 5 weeks: L2 penetrate intestinal wall and migrate to various tissues The larvae encyst and become dormant Larvae become re-infective during pregnancy Larvae re-enter circulatory system and are carried to the placentas They then penetrate through to the fetal bloodstream and complete a lung migration en route to the small intestine for maturation Thus a puppy can be born with the infection Puppies can also become infected from their mother’s milk, but is not commonLife Cycle: Life Cycle If eggs ingested by human or mouse: In these hosts the L2 undergoes developmental arrest They can then wander to various organs and tissues in the body (liver, heart, lung, brain, muscle, eyes)-causing toxocariasis If puppy eats mouse, L2 completes maturation process If dog eats mouse, L2 goes dormant in tissue of dog and may be reactivated during pregnancyPathogenesis in Dogs: Pathogenesis in Dogs Adults are usually asymptomatic Puppies show clinical signs: Noisy breathing and Cough Nasal discharges Vomiting and Diarrhea Stunted growth rate Distended abdomen (pot belly) Pale mucous membranes Death is rare and is due to obstruction of intestine or ulceration and proliferation of intestinal wall Pathogenisis in Humans: Pathogenisis in Humans Many infections are asymptomatic The two main clinical presentations of Toxocariasis: Visceral larva migrans (VLM) Ocular larva migrans (OLM)Toxocariasis: Toxocariasis VLM Occurs mainly in preschool age children Larvae invade multiple tissues including the liver, heart, lungs, brain and muscles Symptoms include: Fever, anorexia, weight loss, cough, wheezing, rash, hepatosplenomegaly, and hypereosinophilia Severe cardiac, pulmonary, or neurologic involvement can occasionally cause deathToxocariasis: Toxocariasis OLM Occurs in older children and young adults Larvae cause inflammation and retinal scarring Symptoms include red eyes and impaired vision May cause partial permanent vision loss or complete blindnessDiagnosis in Dogs: Diagnosis in Dogs All puppies should be assumed to be infected Diagnosis of eggs in feces Eggs are not shed at all times, so false negatives are possibleDiagnosis in Humans: Diagnosis in Humans Detection of antibodies by ELISA Western-blot analysisTreatment in Dogs: Treatment in Dogs Puppies-anthelmintics MebendazoleTreatment in Humans: Treatment in Humans VML-antiparasitic drugs (albendazole or mebendazole) usually along with anti-inflammatory medications Control Measures: Control Measures Wash hands after touching soil or dogs Teach children not to eat dirt or to put dirty objects in their mouths Dogs should be wormed starting when they are 3 weeks old Prevent dog feces from contaminating the environment