ASTHMA ALLAT APOINT CURREBT STUDIES by BADRI

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Added: March 21, 2009 This Presentation is Public 
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Slide1: 1 A PROJECT REPOPRT SUBMITTED BY MET’S INSTITUTE OF PHARMACY, ADGAON (NASHIK)


INTRODUCTION TO ASTHMA: 2 INTRODUCTION TO ASTHMA Asthma is a chronic inflammatory disorder of the airways in which many cells & cellular elements play a role (mast cells, eosinophils, T lymphocytes, macrophages, neutrophils, & epithelial cells). In susceptible individuals , inflammation causes recurrent episodes of wheezing, breathlessness, chest tightness, and coughing, particularly at night/early morning. These episodes are associated with variable airflow obstruction often reversible spontaneously/treatment


Slide3: 3 DIFFERENCE BETWEEN NORMAL AND ASTHMATIC PERSON Airways narrow, caused by: tightening of the muscles that surround the airways swelling of the inner lining, and/or increase in mucus production


CAUSES: CAUSES 4 ENVIRONMENTAL GENETIC B2AR is located on chromosome 5q GENE-ENVIRONMENT INTERACTIONS CD14-ENDOTOXIN REACTIONS ALLERGENS POLLUTION


Pathophysiology : Pathophysiology 5 Inflammation Bronchial smooth muscle Hypertrophy + Mucous glands Hypertrophy Thick mucous Plugging of small airway (bronchoconstriction) Hyper responsiveness to triggers Long period (chronicity)


PATHOPHYSIOLOGY: PATHOPHYSIOLOGY


TRICKS TO COUNTER ASTHMA-: TRICKS TO COUNTER ASTHMA- 7


DRUGS USED FOR TREATMENT: DRUGS USED FOR TREATMENT 8


CONTROLLERS: 9 CONTROLLERS Inhaled glucocorticoid Long-acting inhaled b2-agonists Leukotriene modifiers Theophylline Cromones Anti-IgE Systemic glucocorticoids


RELIEVERS : 10 RELIEVERS


Slide11: 11 Asthma is a problem worldwide, with an estimated 300 million affected individuals Prevalence increasing in many countries, especially in children A cause of a significant number of preventable deaths A major cause of school/work absence EPIDEMIOLOGY


FUTURE SCOPE: FUTURE SCOPE 12 SO WE SHOULD HOPE FOR A BETTER SCOPE


THANK YOU !!: THANK YOU !!


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