synthetic biology


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APPLICATIONS OF SYNTHETIC BIOLOGY FOR HUMAN NEEDS Dr.B.K.Mohanty,Reader in Botany, P.G. Department of Botany &Biotechnology, KHALLIKOTE AUTONOMOUS COLLEGE, BERHAMPUR-760 001,odisha E-mail:-

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THE CHALLENGES OF FEEDING THE WORLDIN2050 A.D In 19 th century, food production was easy, simply by increasing the area under cultivation. In next century, crop productivity was increased mainly by green revolution. In 21 st century, with a projected population of 9.2billion in 2050A.D, food production is to be doubled in 40 years with less resources with sustainability. Added to this ,we have the challenges of climate change, hunger and malnutrition. The technological strategy to integrate best of conventional crop technology with crop biotechnology. FAO has argued to give top priority to food self sufficiency, and food security by using traditional and biotech crops with an aim to conserve natural resources with sustainable use.

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The rapid development in life science and technology has brought a new era in biotechnology. Traditional Biotechnology has played a major role in human welfare without raising an eyelid. Modern fields of biotechnology has rapidly gained priority in the agendas of those in industry, politics, academia and NGO’s because it offers enormous opportunities. It offers to create triple win for people, planet and profit with, Designed and custom made living cells Biological molecules (Novel products) Organisms by transgenic biotechnology GMO, GM-Crops and animals Industrial production of bio-based materials, chemicals and fuels Excellent R&D infrastructure with public-private partnership Social ,environmental and economic benefits of biotechnology From Green revolution to Gene revolution After all these advancements and the tools and techniques (mostly r-DNA technology) available around the world, now the scientists advocate a new frontier in the field of life sciences as ‘SYNTHETIC BIOLOGY’ that is to revolutionize the future of life-forms.

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SUSTAINABLE DEVLOPMENT BY TRIPLE “P” DRIVERS Cost reduction Novel products HURDLES Regulation Further Technology Development Feedstock Prices Investments DRIVERS Knowledge based quality jobs SUSTAINBILITY Drivers Responsibility less energy HURDLES less waste Unawareness Hurdles Acceptance Further technology developments waste management PROFIT Economically Viable PEOPLE Socially Responsible PLANET Environmentally Sound

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The NEW Synthetic biology has the potentials to take us to: Create a bacteria to harvest fuel from sunlight and clean up industrial water It will work as a bio- surveillance agent to track pollution problems Create single celled refineries and factories Creating new life –forms to tackle environmental challenge, food security problems and public health Assembly of off-the-shelf spare parts with tool kits to create novel life forms With application of electronics , nana-biotechnology ,Artificial Intelligence and bio-informatics, there is possibility of creating Robots Assembly of simple circuit using DNA Fibers for molecular sensors Hybrid life forms with nano -circuitry for light harvesting cells However, when all these becomes a reality , the public will ask questions about its safety and impact on the environment Regulations to examine the potential risk and danger of new life –form (SYNTHIA) before they are released to environment

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NOW THE DEBATE S WILL BE ON :- GMO s are not needed to FEED THE WORLD 2. GMO use will not benefit the farmers 3. The techniques involved in genetic modification are not precise. GMOs are not safe. 5. Genetic Engineering poses chance of gene flow to other organisms ( GM crop to non-GM crop ,crop- to -crop or crop- to –wild ) 6. Unintended compositional changes in GM food 7. Public concern of GM products : release, marketing ,labeling , biosafety evaluation and ethical concern 8.The promotion of GM products is due to the greed and self interest of transnational corporations. (Monopoly of products and processes, IPP &IPR)

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