1. Nanomedicine

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Presentation Transcript

Slide 1: 

Nanomedicine: New Hope for Life

Medicine : 

Medicine The Science or practice of diagnosis, treatment and prevention of disease. Limitations: Non specificity Side effects

Slide 3: 

Nanomedicine Nanomedicine can be defined as the monitoring, repairing, construction and control of human biological systems at the cellular level by using materials and structures engineered at the atomic or molecular level

Slide 5: 

Important Characteristics of Nanoparticles : Target specificity Extreme small size Encapsulation efficiency Carry high concentrated drug Zeta potential (surface charge) Efficient drug release

Nanoparticles : 

Nanoparticles Metal Nanoparticles: Gold Particle Quantum Dots Polymeric Nanoparticles Dendrimer Nanopores Nanotubes Liposomes

Slide 7: 

IMAGINARY WORLD OF NANOMEDICINE!

Nanoparticles in Cancer therapy : 

Nanoparticles in Cancer therapy

Slide 10: 

Liposomal Drug Delivery in Breast Cancer Diffusion Endocytosis

Multicomponent Targeting Strategies : 

Multicomponent Targeting Strategies

Slide 12: 

Drug Transport and Release Pathway

Slide 13: 

Liposomal Drug Delivery causes Cancer Cell Death

Slide 14: 

Quantum Dots Inorganic semiconductor nanocrystals Diameter between 2-8 nm High resolution contrast agent for Medical Imaging Reduced tendency to Photobleach Generally composed of atoms from groups II and VI elements (e.g. CdSe and CdTe) or groups III and V elements (e.g. InP and InAs) of the periodic table.

Slide 15: 

Quantum Dot

Slide 16: 

Fluorescent Photostability of Quantum dot Compared with Organic Dye Alexa

Slide 17: 

Multifunctional QDs targeting Tumor Cells. QDs are conjugated to various affinity ligands (peptide, antibody, inhibitor, drug etc.) specific for the Tumor Cell Biomarkers.

Slide 18: 

Various strategies for conjugating antibodies/proteins to QDs.

Slide 19: 

Nanorobot A Future Vision

Slide 20: 

THANK YOU

Slide 21: 

Gold Nanoparticle

Slide 22: 

Dendrimer

Slide 23: 

Nanopores

Slide 24: 

Nanotubes

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