CRP 1000 Presentation

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EGF cytokine complex Increasing skin renewal and regeneration The secret of skin rejuvenation

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CRP 1000 - Skin Repair Innovation

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Developed by:

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Swiss Public Limited Company founded in December 2004 Headquarters near Zurich / in Wetzikon (Switzerland) Development and production of all products in Switzerland Focused on Skin Care & Beauty 4 Swiss Skin Science Labs

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Swiss Skin Science Labs Wetzikon

CRP 1000 Skin Repair : 

CRP 1000 Skin Repair Innovative skin repair technology from Switzerland CRP - 1000. is very effective for wounded skin, mature skin and impure skin. CRP a unique skin care product line, developed in Switzerland, using special technology and know how. CRP 1000 The SKIN REPAIR Revolution!

MANUFACTURING - ISO 9001 : 2000 certified : 

CRP - REPAIR PRODUCTS are manufactured under most modern facilities. Qualified personal, high standard laboratories and up-to-date know how guarantee the high quality of the CRP - SKIN REPAIR products. The manufacturing facilities are in Switzerland. MANUFACTURING - ISO 9001 : 2000 certified

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CRP 1000 can be used as topical daily nutritive essence serum for following treatments: Iontophoresis Phonophoresis Electroporation Meso-Cosmoceutical purposes, TDS (Transdermal Delivery System) Treatments Skin rejuvenation with 1 product:

CRP 1000 Component: 

CRP 1000 Component CRP 1000 includes a balanced mixture of fundamental factors in blood that help recover the normal physiology of the skin.

CRP 1000 Component: 

CRP 1000 Component Sterile biological solution sterile based on 8 groups of active ingredients: 1. Vitamins: 16 (A, E, C, D, B, K …) 2. Amino acids: 24 [ arginine, hydroxyproline…] 3. Minerals: Mg, Ca, Na, K 4. Coenzymes: CoA, Cocarboxylase… 5. Nucleic acids: DNA, RNA… 6. Cytokines: EGF, bFGF 7. Peptide: Copper Peptide 8. Reducing Agent : Gluthation

Vitamins conc. mg/L: 

Vitamins conc. mg/L Ascorbic Acid (vit.C) 60 Retinol (vit.A) 0,25 Menadion (vit.K) 0,025 Riboflavin (vit.B2) 0,025 Calcium pantothenate (vit.B5) 0,025 Choline (vit B7 or J) 1,25 Tocopherol (vit.E) 0,025 Calciferol (vit D2) 0,025 vit. A

Vitamins conc. mg/L: 

Vitamins conc. mg/L Thiamine (vit.B1) 0,25 Niacin (vit. PP) 0,0625 Pyridoxine (vit.B6) 0,0625 Biotin (vit.B1) 0,025 Folic acid (vit.B9) 0,025 Vitamin B12 0,25 Aminobenzoic acid (vit.B10) 0,125 Inositol (vit.I) 0,125 vit. B1

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Amino acids conc. mg/L Aminobutyric acid  60 Alanine 32 Glycine 14 Isoleucine 18 Methionine 4 Proline 6 Threonine 19 Valine 25

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Amino acids conc. mg/L Aspartic acid 10 Arginine 31 Cystine 10 Hydroxyproline 4 Leucine 20 Ornithine 7 Serine 11 Trytophane 18

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Amino acids conc. mg/L Glutamic acide 8 Asparagine 8 Glutamine 13 Histidine 20 Lysine 31 Phenylalanine 17 Taurine 4 Tyrosine 16

Minerals conc. mg/L: 

Minerals conc. mg/L Calcium 200 Potassium 400 Magnesium 100 Sodium 6600

Coenzymes conc. mg/L: 

Coenzymes conc. mg/L Coenzyme A 2,50 Cocarboxylase 1 NAD 7 FAD 1 NADP 1 UTP 1 (NAD+)

Nucleic acids conc. mg/L: 

Nucleic acids conc. mg/L Deoxyadenosine 10 Deoxycystidine 10 Methylcytosine 0,1 Deoxyguanosine 10 Thymidine 10

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Cytokines conc. mg/L Epidermal Growth Factor (EGF) 1 basic Fibroblast Growth Factor (bFGF) 1 EGF bFGF

Peptide conc. mg/L: 

Peptide conc. mg/L Copper peptide 10 Reducing Agent conc. mg/L Gluthation 10

Biological effects of CRP 1000: 

Biological effects of CRP 1000 Vitamins provide an anti-deficiency function Amino acids a better protein construction Minerals guarantee the ionic balance Co-enzymes activate the biochemical reactions Nucleic acids stimulate synthesis Cytokines (EGF, bFGF) stimulate cell functions in aged skin Copper Peptid increases biosynthesis of collagen and elastin Reducing Agent Gluthation : Super anti-oxidant created from liver

In vitro study : 

In vitro study Evaluation of the cellular stimulation properties of CRP 1000 on human skin fibroblasts +11% ~ +30% after 72 hours +12% ~ +37% after 168 hours

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Rejuvenating Improvement in Skin Firmness and Elasticity (%) After 21 days Formulation containing (0.5% Cytokines complex) Cytokines complex causes Improvement in Skin Firmness and Elasticity Placebo

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Wound healing 0.5% Cytokines complex stimulates Cell Metabolism 0.5% Cytokines complex stimulates Protein Biosynthesis Absorbance (570nm) Concentration (pg/ml) Concentration (pg/ml) 200 0.2 0.4 0.6 200 5% 50 10% 100 400 800 1600 Absorbance (570nm)

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0.5% Cytokines complex stimulates Collagen Synthesis Concentration (pg/ml) Stimulation of Collagen Synthesis (Collagen ELISA) 135 140 145 Wound healing 150 155 160

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Rejuvenating Formulation containing (0.5%Cytokines complex) Formulation containing (0.5%Cytokines complex)

Regeneration: 

Regeneration CRP 1000 restores the natural skin repair mechanism. CRP 1000 induces the proliferation and reconstitutes the optimum functional capability of prematurely senescent fibroblasts. CRP 1000 facilitates the reconstruction of the cutaneous architecture through an active action on collagen fibres.

Regeneration: 

Regeneration 1. Action on Fibroblasts Fibroblast Growth Factor – like activity Favors the correct assembly of the fibronectin extra cellular matrix. Cultured senescent fibroblasts acquiring an arrangement and morphology similar to those of young fibroblasts.

Regeneration: 

Regeneration 2. Reconstruction of cutaneous architecture Collagenase activity on denatured collagen Copper Peptide activity on increase of biosynthesis of collagen and elastin Provides a structural support network of fibronectin

Protection: 

Protection CRP 1000 potentates the protective mechanism of the skin Reducing agent Gluthation : Super anti-oxidant created from liver Reinforced with antioxidant : Vit C, Vit E

Combination Treatment: 

Combination Treatment CRP 1000 can be used as topical daily nutritive essence serum.

Combination with TDS(Transdermal Delivery System) Treatment: 

Combination with TDS (Transdermal Delivery System) Treatment CRP 1000 with Iontophoresis

Combination with TDS(Transdermal Delivery System) Treatment: 

CRP 1000 with Phonophoresis Combination with TDS (Transdermal Delivery System) Treatment

Combination with TDS(Transdermal Delivery System) Treatment: 

CRP 1000 with Electroporation Combination with TDS (Transdermal Delivery System) Treatment

Combination Treatment: 

Combination Treatment CRP 1000 can be used as topical daily nutritive essence serum after peeling (laser peel, chemical peel, dermabrasion, etc.).

Combination Treatment: 

Combination Treatment CRP 1000 can be compatible with botox® treatment and with fillers (Matridex, Matredur, etc.).

A natural activator of repair and regeneration of skin damaged by:: 

A natural activator of repair and regeneration of skin damaged by: Topical Retinoids Repairs skin problems caused by retinoids, restoring skin integrity. For acne (both male and female skin) Photoaging Eyes and lip contour

A natural activator of repair and regeneration of skin damaged by:: 

A natural activator of repair and regeneration of skin damaged by: Ablative and non-ablative rejuvenation techniques Post-treatment care for rapid cutaneous repair Post-treatment care for Laser and peeling techniques

A natural activator of repair and regeneration of skin damaged by:: 

A natural activator of repair and regeneration of skin damaged by: Photoaging Reactivate natural skin regeneration, improving cell functionality

Before and after pictures with CRP 1000 and TDS:: 

Before and after pictures with CRP 1000 and TDS: CRP 1000 + BioViso Result after 4 treatments with CRP and electrotherapy

Before and after pictures with CRP 1000 and TDS:: 

Before and after pictures with CRP 1000 and TDS: CRP 1000 + BioViso Result after 4 treatments with CRP and electrotherapy

Before and after pictures with CRP 1000 and TDS:: 

Before and after pictures with CRP 1000 and TDS: CRP 1000 + Acthyderm Result after 5 treatments with CRP and BioCell, application with electroporation

Before and after pictures with CRP 1000 and TDS:: 

Before and after pictures with CRP 1000 and TDS: CRP 1000 + Acthyderm Result after 6 treatments with CRP and BioCell , application with elecptroporation

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A NEW DUAL TREATMENT OFFERING AN INTEGRAL SOLUTION TO HAIR LOSS

CRP 1000 Profile: 

CRP 1000 Profile Anti-hair loss Balanced combination of renowned, effective and innovative components in high concentrations Patients profile Patients with all type of Alopecias

ALOPECIAS: 

ALOPECIAS Alopecia is a source of constant investigation Alopecia is an important concern for dermatologists First treatments were targeted to prevent hair loss only. New elements were introduced to stimulate hair growth Nowadays, a proper treatment is expected to also protect hair structure and integrity.

CRP 1000: 

CRP 1000 A balanced and comprehensive combination of highly effective and innovative components able to act against all factors promoting hair loss. Acts on the hair life cycle at different levels. Prevents hair loss Normalizes hair grease secretion Stimulates hair growth Protects hair structure & integrity

Prevents hair loss: 

Prevents hair loss Prevents the death of hair follicle Normalizes hair greasy Prevents the miniaturization of the bulb and the death of the hair follicle

Protect hair integrity: 

Protect hair integrity Enzimatic activity against Superoxide Anions(O-) inhibits lipid peroxidation Vitamin C: Hydrosoluble antioxidant Vitamin E: Liposoluble antioxidant Reducing agent Gluthation : Super anti-oxidant created from liver Protect hair integrity

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CRP 1000 the most innovative skin repair product ever created!

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EGF cytokine complex Increasing skin renewal and regeneration Thank you for your attention