4-schistosoma

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Medical Parasitology:

Medical Parasitology Prof. Dr : Ahmed Bayoumy Professor of Parasitology Al-Azhar Faculty of Medicine

TREMATODA:

TREMATODA Hepatic flukes Fasciola hepatica Fasciola gigantica Intestinal flukes Heterophyes heterophyes Blood flukes Schistosoma sp.

Blood flukes:

Blood flukes Schistosoma haematobium mainly in upper part of Egypt Schistosoma mansoni mainly in lower part of Egypt (Delta)

Habitat:

Habitat S. haematobium in pelvic and vesical venous plexus S. mansoni in branches around the colon

Copula of Schistosoma:

Copula of Schistosoma

S. mansoni:

S. mansoni

S. haematobium:

S. haematobium

Life cycle:

Life cycle

Life cycle of Schistosoma sp.:

Life cycle of Schistosoma sp. Adults live in the portal circulation (pelvic and vesical venous plexus) or (around the colon). They lay mature eggs which pass with urine or stool after penetration of blood vessels and tissues. Egg much reach water canal. Hatching occur producing miracidum. Miracidia invade suitable snail ( Bulins or Biomphalaria).

Life cycle of Schistosoma sp.:

Life cycle of Schistosoma sp. In the snail the parasite undergoes several developmental stages (sporocyst , daughter sporocyst and cercaria). Cercariae leave the snail (infective stage). Penetration of skin is the mode of infection. after penetration they travel through the venous circulation to the heart, lungs and change to adults in portal circulation.

Snails (intermediate host):

Snails (intermediate host)

Infective stage:

Infective stage

Mode of infection:

Mode of infection Penetration of skin

Diagnostic stage:

Diagnostic stage

Slide15:

Pathogenesis (schistosomiasis)

Schistosoma haematobium:

Schistosoma haematobium Dermatitis Allergic manifestation (urticaria) Enlarged tender liver Terminal hematuria Dysuria Anemia Bladder fibrosis Stone formation Cancer bladder

dermatitis:

dermatitis

Allergic manifestations:

Allergic manifestations

Hematuria:

Hematuria

Schistosoma mansoni:

Schistosoma mansoni Dermatitis Allergic manifestation Enlarged tender liver Abdominal pain Dysentry Anemia Heptosplenomegaly Liver cirrhosis Ascites Esophageal varices

cirrhosis:

cirrhosis

Hepatosplenomegaly and Ascites:

Hepatosplenomegaly and Ascites

Growth Retardation:

Growth Retardation

Diagnosis :

Diagnosis Clinical picture Direct Urine ex for S.haematobium Stool ex for S. mansoni Indirect Serological test

Treatnent :

Treatnent Praziquantel (distocid) Commiphora molmol (mirazid)

Prevention and control:

Prevention and control Sanitary disposal system Protection from cercarial infection Wearing boots and gloves Drying of wet part after swimming in canalas Health education Mass treatment Snail eradication

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