Anti-Human BAFF Therapeutic Antibody

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Anti-Human BAFF Therapeutic Antibody

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Tabalumab TAB-216 DESCRIPTION CATALOG SIZE Anti-Human BAFF Therapeutic Antibody TAB-216 1mg PRODUCT INFORMATION  Product Overview  Recombinant monoclonal antibody to BAFF. Tabalumab LY 2127399 is an anti- B-cell activating factor BAFF human monoclonal antibody designed for the treatment of autoimmune diseases and B cell malignancies.  Target  BAFF  Type  IgG4 - kappa  Immunogen  The details of the immunogen for this antibody are not available.  Species Reactivity  Human  Expression Host  CHO  Applications  Suitable for use in WB FC IP ELISA Neut FuncS IF and most other immunological methods.  CAS  1143503-67-6  Specificity  Tested positive against native human antigen.  Protein Construction  Immunoglobulin G4 anti-human cytokine BAFF human monoclonal LY2127399 γ4- chain disulfide with human monoclonal LY2127399 kappa-chain dimer  Molecular Weight

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 146250  Purity  97 by SDS-PAGE under reducing conditions and visualized by silver stain.  Size  1mg  Storage  4°C. For long term storage aliquot and store at -20°C. Repeated thawing and freezing must be avoided. BACKGROUND  Antigen Description  Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor BAFFR/BR3 promotes the survival of mature B-cells and the B-cell response.  Function  cytokine activity protein binding receptor binding tumor necrosis factor receptor binding  Gene ID  10673  Synonyms  TNFSF13B tumor necrosis factor ligand superfamily member 13b TNFSF20 tumor necrosis factor ligand superfamily member 13B BAFF BLYS CD257 TALL 1 TALL1 THANK delta BAFF Delta4 BAFF B-lymphocyte stimulator B-cell-activating factor ApoL related ligand TALL-1 TNF homolog that activates apoptosis dendritic cell- derived TNF-like molecule tumor necrosis factor-like protein ZTNF4 TNF and ApoL- related leukocyte expressed ligand 1 tumor necrosis factor ligand superfamily member 20 DTL ZTNF4 TALL-1 Related Products  TAB-206  Anti-Human CTLA4 Therapeutic Antibody  TAB-726

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 Anti-ACVR2B Therapeutic Antibody  TAB-245  Anti-Human CD3 epsilon Therapeutic Antibody  TAB-106  Anti-Human EPCAM Therapeutic Antibody  TAB-759  Anti-CD40 Therapeutic Antibody  TAB-770  Anti-PDCD1 Therapeutic Antibody OPDIVO  TAB-717  Anti-APP Therapeutic Antibody  TAB-H44  Anti-Human CSF2 Therapeutic Antibody  TAB-767  Anti-endotoxin Therapeutic Antibody  TAB-020  Anti-Human EGFR Therapeutic Antibody Vectibix

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