Building Block Synthesis


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Building Block Synthesis


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slide 1:

Building Block Synthesis During the last decades the synthesis of building blocks has been explored by numerous groups which are used in pharmaceutical products and other biologically active substances. Building blocks are important intermediates for many drugs and have major significance in the discovery and synthesis of drugs. Many important substances and some significant effect of natural drugs and synthetic drugs such as chlorophyll heme and nucleic acid contain heterocyclic structure. The heterocyclic compounds or heterocyclic compounds containing nitrogen atoms or fluorine atoms can be introduced into building blocks. Further building blocks as intermediates can be used to synthesize the subsequent drugs or compounds which can improve or change the properties of the drugs or compounds. In addition the introduction of sulfur and nitrogen-containing sulfonamide on the molecules of isopimaric acid can wide the range of effective anti- cancer activity of isopimaric acid. In a word some necessary group can be introduced into building blocks and change the properties of subsequent compounds. Our Available Building Block Synthesis Method include but not limited to the following:  Biological routine Biocatalysis which is applying enzymes for organic synthetic transformations has become a common applied green technology for selected asymmetric transformations. Because the biodegradability of the catalyst and the benign reaction conditions eliminate toxic reagents and solvents it can reduce the manufacturing costs and the environmental impact. Biocatalytic preparations are important methods for synthesis of building blocks with high optical purity. Biocatalysis can be used in the synthesis of enantiopure building blocks for pharmaceuticals.

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 Chemical routine Using some familiar compounds to introduce the structure that you want into building blocks is a simple and easily controlled method. Fluorine-containing building blocks heterocyclic-containing building blocks aromatic-containing building blocks and nitrogen-containing building blocks can be synthesized by chemical routine. For example with simple and efficient chemical routine simple fluorine-containing building blocks are synthesized and subsequently different fluorine heteroyclic compounds can be synthesized. Finally they can be applied to synthesize fluorinated drugs or convert to other fluorinated heterocyclic compounds. Why Choose BOC Sciences BOC Sciences can provide various types of methods to help you synthesize building block whatever group or chemical constitutions you want to introduce. We are expert at designing the routine and using multiple techniques NMR LCMS GCMS and X-ray to analyze compounds after the building block synthesis completed. The time of building block synthesis is very fast with your demand.

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